Marie Gudme Leth was born in Arhus, Denmark in 1910. She studied fine arts at the Copenhagen Royal Art Academy. From 1931 to 1948 she is in charge of the textile department at the Art Craft School of Copenhagen. In 1934 she visited a German textile factory that used a new printing process: screen-printing. That process allowed the printing of fabric at a avery low cost. In 1935 she was one of the founders of the Dannish testile company, Dansk Katttuntrykkeri. For the first time Danish printed fabrics appeared in ordinary Dannish homes. She designed many floral pattern fabrics.